Raman Mapping Of Pharmaceuticals. Study of Pharmaceutical Tablets Using Raman Mapping. Characterization and Mapping of active pharmaceutical ingredients and excipients in a tablet by Raman and infrared spectroscopy on the same microspectrometer.
Raman spectroscopy is becoming one of the most popular analytical measurement tools for pharmaceutical applications ranging from verification of raw materials to process monitoring of drug production to quality control of products. The below image shows a map showing blending of a compound on the left and on the right a reference spectra of the blend. This can confirm the identity and presence of specific components and reveals their location and distribution within a sample.
Characterisation and Mapping of active pharmaceutical ingredients and excipients in a tablet BY RAMAN and infrared spectroscopy on the same microspectrometer The objective of the measurements is to identify the unknown components and their respective dispersion within pharmaceutical tabs by Raman and FT-IR microspectrometry.
Raman mapping of drug products is also a very useful way to probe for patent infringement whether it be to find evidence of an infringing polymorph or to detect coatings or co-localization of ingredients defined in the patent. Raman mapping is a powerful and emerging tool in characterization of pharmaceuticals and provides non-destructive chemical and structural identification with minimal sample preparation. Raman mapping is a powerful technique and is. 45 Also rapid imagingclassification of drug.
